Causes of Osteoarthritis [How to Prevent Osteoarthritis?]
One of the most common degenerative joint disorders is osteoarthritis (OA). Patients often tell their doctors, “I cured my osteoarthritis,” & then look for ways to make this hope come true. The causes of osteoarthritis are unclear despite ongoing research. However, a combination of mechanical & biological factors may cause the condition.
Let’s examine the causes of osteoarthritis, as well as its stages, symptoms, diagnosis, how to prevent osteoarthritis & the available treatments.
Osteoarthritis Pathophysiology
Understanding the pathophysiology of osteoarthritis is essential for effective treatment. As the cartilage deteriorates (due to the release of proinflammatory cytokines & enzymes & the formation of osteophytes, or bone spurs), it becomes rigid & brittle, resulting in pain & movement restriction. Over time, cartilage may deteriorate completely, causing bones to rub directly against one another.
Pain is the primary osteoarthritis symptom, particularly after prolonged activity. Additional osteoarthritis symptoms include:
- Stiffness, particularly upon waking up or being inactive
- Tenderness when mild pressure is applied
- Loss of flexibility
- A grating sensation while in motion or Crepitus
- Swelling (or inflammation) around the joint
Different joints cause different types of osteoarthritis:
- Knee Osteoarthritis: The most common type, which affects millions worldwide.
- Hip Osteoarthritis: This affects the hip joint & can affect walking ability.
- Hand Osteoarthritis: Affects the thumb’s base & the individual fingers.
- Spine Osteoarthritis: Targets the neck & lower back.
Causes of Osteoarthritis
OA is the primary cause of chronic disability among the elderly. The disease primarily affects weight-bearing joints, such as the knees, hips, cervical & lumbar spines, & feet. Also frequently affected are the distal interphalangeal (DIP), proximal interphalangeal (PIP), & first carpometacarpal (CMC) joints.
The common causes of osteoarthritis, such as:
- Aging: Age-related changes in collagen matrix traits such as declines in chondrocyte responsiveness, decreased lubricating fluid inside the joints, & dropped repair ability worsen cartilage deterioration, an indicator of OA.
- Joint Injuries & Mechanical Stress: A joint injury from sports, work, or accidents can be one of the primary causes of OA in old age. According to a study, knee injuries raise knee OA risk six-fold.
- Obesity: Joint cartilage wears down more quickly when there is more stress on weight-bearing joints like the knees, hips, & lower back.
- Genetics: Some individuals have a genetic predisposition to develop OA. Evidence from familial & twin research points to an inheritance factor, although the genes responsible have yet to be identified.
- Bone deformities: Malformed joints or damaged cartilage may affect a person’s risk of developing OA from birth.
- Certain Occupations: Occupations involving repetitive stress on specific joints can increase the risk or predispose joints to an accelerated onset of OA.
What are the 4 Stages of Osteoarthritis?
Stage |
What Is It |
Symptoms & Signs |
Diagnosis |
Treatment |
Stage 0
(Pre-Osteoarthritis) |
Normal, healthy joints or cellular damage from early OA. | No symptoms to note; potential alterations to the joint lining. | MRI examination | OTC medications, supplements, lifestyle changes |
Stage 1
(Early or Doubtful) |
Early OA, minor cartilage loss, & bone spur development. | Some may experience mild pain, & cartilage loss begins. | Physical exam, MRI, X-rays, laboratory tests | Lifestyle changes, supplements, OTC medications |
Stage 2
(Mild or Minimal) |
Growth of bone spurs & minor cartilage degeneration. | Increased activity-induced pain, rigidity, & mobility restriction. | X-rays, symptoms assessment, physical exam | NSAIDs, lifestyle changes, low-impact exercises |
Stage 3 (Moderate) | Cartilage wear & visible joint space constriction. | Constant pain, morning stiffness, & joint swelling | Symptoms assessment, physical exam, X-rays, MRI | NSAIDs, pain medication, injections, physical therapy |
Stage 4 (Severe) | Significant cartilage loss & joint degeneration. | Severe pain, activity restriction, stiffness, & inflammation. | Symptoms assessment, physical exam, lab tests, X-rays, MRI | Osteotomy, arthroplasty (joint replacement) |
Osteoarthritis Diagnosis, Treatment & Preventive Measures:
A comprehensive medical history, physical examination, & imaging tests, such as X-rays or MRI, are necessary for an accurate osteoarthritis diagnosis.
Depending on the disease’s stage & severity, conservative treatments like physiotherapy or surgical procedures can help alleviate pain & enhance joint function. Dr. Sameep Sohoni, an Orthopedic Doctor in Thane, provides sophisticated osteoarthritis treatment solutions to meet patients’ demands.
How to prevent osteoarthritis is as follows:
- Maintaining a healthy weight relieves strain on weight-bearing joints.
- Keep Active while engaging in regular exercise to strengthen the muscles surrounding the joints.
- Alternate between repetitive tasks or use (or wear) joint protection to prevent chronic stress.
- Wear protective gear when engaging in sports to prevent accidents.
Conclusion
Understanding the “causes of osteoarthritis” & its impacts can aid patients & medical professionals in managing this degenerative condition. Although complete solutions are unusual, symptomatic relief & functional restoration are attainable due to modern medical advancements.
Dr. Sameep Sohoni – The Best Joint Replacement Surgeon in Thane
Dr. Sameep Sohoni, a renowned Knee Replacement Surgeon in Thane, is an expert in robotic knee replacement surgery, providing remarkable results & patient satisfaction. He’s the most famous orthopedic specialist, with over 12,000 patients & 12 years of experience in robotic joint replacement, fracture surgery, bone & joint disorders, sports injuries, & arthritis treatment.
If you are experiencing osteoarthritis symptoms, consult with Dr. Sameep Sohoni, a Joint Replacement Surgeon in Thane, who has extensive experience diagnosing & treating osteoarthritis. He will provide you with expert guidance & treatment options to manage your symptoms & enhance your quality of life.
Reference
- https://www.hopkinsarthritis.org/arthritis-info/osteoarthritis/oa-pathophysiology/
- https://www.mayoclinic.org/diseases-conditions/osteoarthritis/symptoms-causes/syc-20351925
- https://pubmed.ncbi.nlm.nih.gov/31072840/
- https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/joint-disorders/osteoarthritis-oa
- https://www.arthritis.org/diseases/osteoarthritis